Fig. 4

YPF promoted the DCs maturation through the JAK2-STAT3 pathway. (A,B) JAK2-STAT3 pathway in tumor and paracancerous tissues. (C,D) JAK2-STAT3 pathway in mouse bone marrow-derived DCs induced by normal culture medium or tumor supernatant. Data are presented as the means ± SD.*P < 0.05 and **P < 0.01 vs. Model group; #P < 0.05 and ##P < 0.01 vs. Control group.