Fig. 1 | Scientific Reports

Fig. 1

From: A novel lncRNA AC112721.1 promotes the progression of triple-negative breast cancer by directly binding to THBS1 and regulating miR-491-5p/C2CD2L axis

Fig. 1

AC112721.1 was highly expressed in TNBC and associated with poor prognosis. (A) Venn Diagram showed the number of genes that were significantly differentially expressed in four subtypes of breast cancer. (B) Venn Diagram showed the number of genes that were significantly associated with survival time in four subtypes of breast cancer. (C) The expression levels of AC112721.1 in TNBC tissues (N = 163) and normal tissues (N = 61) in the TCGA database. (D) Kaplan-Meier survival analysis of TNBC patients stratified by AC112721.1 expression level. (E) ROC curves were used to determine the diagnostic value of AC112721.1 expression in TNBC based on TCGA data. (F) The relative expression of AC112721.1 was detected by qRT-PCR in TNBC tissues (N = 14) and paracancer tissues (N = 15) (Wilcoxon test). N, number. *p < 0.05.

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