Fig. 1 | Scientific Reports

Fig. 1

From: KRT7 promotes pancreatic cancer metastasis by remodeling the extracellular matrix niche through FGF2-fibroblast crosstalk

Fig. 1

Identification of KRT7 as a differentially expressed gene. (A) Volcano plot (|log2FC| > 1, P value < 0.05) of the GSE71729 data. (B) Volcano plot (|log2FC| > 1, P value < 0.05) of the TCGA-PDAC data. (C) Volcano plot (|log2FC| > 1, P value < 0.05) of the GSE151580 data. (D) Venn diagram of the overlapping DEGs among the GSE71729, TCGA and GSE151580 dataset. (E) Differential mountain maps of PDAC samples according to proteomics. (F) Venn diagram of KRT7 overexpression data. (G) OS probability curve of patients stratified by KRT7 expression according to data from the KM plotter database. (H) OS and DFS curves of patients stratified by the median KRT7 expression level according to data from the GEPIA2 database. (I) OS and DFS curves of patients stratified by KRT7 expression quartiles according to data from the GEPIA2 database. (J) The expression of KRT7 in tumor and normal tissues according to data from the GEPIA2 database. (K) The expression of KRT7 in patients with PDAC of different AJCC stages according to data from the GEPIA2 database.

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