Fig. 1 | Scientific Reports

Fig. 1

From: Mechanism of miR-200b-3p-induced FOSL2 inhibition of endometrial cancer cell proliferation and metastasis

Fig. 1

The mRNA and protein expression levels of FOSL2 in EC cells and the targeted binding sites of miR-200b-3p with the FOSL2 3′-UTR. (A) Expression of miR-200b-3p in EC cell lines; (B) Semi-quantitative analysis of FOSL2 mRNA expression in EC cell lines; (C) Protein expression levels of FOSL2 in EC cell lines and semi-quantitative analysis; bP < 0.01 versus hEM15A cell. (D) Target binding sites of miR-200b-3p in the 3′-UTR of FOSL2; (E) Expression of miR-200b-3p in various groups of cells; dP < 0.01 versus NC-inhibitor group. (F) Expression of FOSL2, ETV1, EGFR in various groups of cells; fP < 0.01 versus NC-mimic group; jP < 0.01 versus NC-inhibitor. (G) Results of dual luciferase assay. fP < 0.01 versus NC-mimic group; hP < 0.05 versus NC-mimic group.

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