Fig. 1

Exemplary cases of an healthy individual (A) and a participant with intermediate age-related macular degeneration (B) with (from left to right) confocal near-infrared en-face imaging, the horizontal OCT line through the fovea and a heat-map representation of the spatial association of the relative ellipsoid zone reflectivity (rEZR) and retinal sensitivity as tested by mesopic fundus-controlled perimetry (FCP). In the heat-map representation, the rEZR (AU) is represented in the background with lower and higher values ranging from red to green, while point-wise retinal sensitivity is demonstrated by superimposed specific values (dB) and also color-coded stimulus points, again with lower values in red and higher values in green. Note the association of lower rEZR values (more red-colored areas) with worse retinal function, as well as higher rEZR values (more green-colored areas) with better retinal function.