Fig. 11

Molecular docking verification of HMOX1 and PIK3CG with related drug small molecule components. (A–E) Anoikis exhibits sensitivity to the drugs dihydrorotenone, OF-1, ibrutinib, SB505124, and P22077. (F) LDCD shows sensitivity to SB505124. (G–J) Schematic diagrams of molecular docking (black circles represent binding pockets, and dashed lines of different colors represent potential weak interactions between ligands and amino acid sites).