Fig. 1

CBS knockdown exaggerated experimental colitis induced by DSS. (A) Representative western blot images of CBS in mice colon epithelial cells. (B) Relative band density of CBS in western blot. (C) Treatment overview of C57/BL mice induced by 3.5% DSS. (D, E) Survival rate of WT and CBS +/− mice. (F, G) Body weight changes of WT and CBS +/− mice. (H) Comparison of weights between WT and CBS + /- mice of DSS group. (I) Comparison of weights between WT and CBS +/− mice of DSS + GYY4137 group. (J, K) The DAI score of WT and CBS +/− mice.