Fig. 3
CBS-H2S axis sustained proliferation of intestinal epithelial organoids in mice. (A, B) Colon intestinal tissue organoids growth status of WT and CBS +/− mice. (C) The number of total organoids statistics of WT and CBS +/− mice from day 2–10. (D) The number of total buddings organoids of WT and CBS +/− mice from day 2–10. (E) The number of single budding organoids of WT and CBS +/− mice from day 2–10. (F) The number of multiple budding organoids of WT and CBS +/− mice from day 2–10. (G, H) The percentage of organoids of WT and CBS +/− mice from day 2–10. (I, J) The Cyst-like organoids of WT and CBS +/− mice at day 10. (K, L) The statistics of normal and cyst-like organoids of WT and CBS +/− mice from day 2–10. (M) FD-4 flux of WT and CBS +/− organoids at day 10.
