Fig. 8 | Scientific Reports

Fig. 8

From: Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches

Fig. 8

In vivo antitumor effect of compound 27. (A) Changes in tumor size in loaded mice. (B) Tumor growth curves in loaded mice. (C) Tumor inhibition rate. (D) Survival curves. (E) H&E staining of tumor tissues It is used to observe the morphology and structure of tumor cells, and to analyze whether compound 27 causes changes such as necrosis and apoptosis of tumor cells (magnification ×100). (F) H&E staining of tumor tissues and organs To evaluate the potential toxicity and side effects of compound 27 on normal tissues and organs, ensuring anti-tumor and reducing normal tissue damage (magnification ×100).The numerical values are expressed as mean ± standard deviation (n = 6) and compared with the control group, *p < 0.05, **p < 0.01, #p < 0.05, ##p < 0.01.

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