Fig. 9 | Scientific Reports

Fig. 9

From: Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches

Fig. 9

RNA sequencing data analysis results. (A) Heatmap of differentially expressed genes in TCGA dataset. (B) Heatmap of the expression patterns of all DEGs. Horizontal coordinates in the graph indicate sample names and clustering results of samples, and vertical coordinates indicate differential genes and clustering results of genes. Colors represent gene expression in sample level log2 (FPKM + 1). (C) GO enrichment analysis. (D) Enrichment histogram of DEGs in KEGG pathway. The horizontal coordinate is GeneNum, the number of relevant genes annotated in the entry, and the vertical coordinate is for each pathway entry. The color of the histogram represents the p-value of the hypergeometric test. (E) Venn diagram demonstrates the intersections of genes between DEGs data and Targets data.

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