Fig. 9

Acute renal failure (ARF) induced by gentamicin (GN) in rats: effects of conventional, nanoparticle (NP), and combination forms of glutathione (GSH) and Lepidium sativum (LS) on tissue levels of neutrophil gelatinase-associated lipocalin (NGAL) and Kidney injury molecule-1 (KIM-1). The data shown are the means with standard error of the mean (n = 6). ap < 0.0001 in comparison to the control group. ****p < 0.0001 in comparison to the ARF-induced group. #p < 0.05 and ####p < 0.0001 when compared with the related nanoparticle group. $p < 0.05 when comparing the LS and LS-NP groups to the GSH and GSH-NP groups, respectively. Non significance (p > 0.05). CS chitosan, O LS-GSH combination, GSH-NP glutathione nanoparticles, LS-NP Lepidium sativum nanoparticles, O-NP LS-GSH nanoparticle combinations.