Fig. 1

PSD3 is dramatically up-regulated in ESCC. A, B, Volcano plots of differential proteins between PKM2 mutants and wild-type PKM2; X1 represents KYSE-150, X2 represents R399E, X3 represents K367M. C, IHC staining results of PSD3 in ESCC tissues and NATs. D, PSD3 mRNA expression levels in common tumors were analyzed by GEPIA database. E, Effect of PSD3 on overall survival of ESCC patients. F, Effect of PSD3 on the overall survival of ESCA patients was analyzed by GEPIA database.