Fig. 4
From: Novel kinetic and developmental transcriptomic pan-stress responses by embryonic stem cells
WNT5B and FZD8 are a probable ligand-receptor pair induced significantly and highly by all seven stimuli38,39. Projected protein–protein interaction for agonistic and antagonistic interactions of WNT5B and FZD8 (yellow circles) are shown for weak embryotoxic stressors (A–D), ND (E) and strong embryotoxic stressors (F, G). See red (upregulated) and blue (downregulated) gene names and (A) (activation) and (B) (binding) interaction lines. Figure modified from in silico cross-referencing of RNAseq analysis by Advaita iPathway40.
