Fig. 4
From: Windows of susceptibility to neonatal acute kidney injury and nephron loss in a rabbit model
Late-exposed rabbits at 6 weeks of age express overall higher percentage of Kim1, with overlapping staining of injury marker Krt8. A RNAScope imaging of early exposed rabbit and B late-exposed rabbit at lower magnification and higher magnification (C–D). Co-staining of Kim1 and Krt8 on tissue can be seen in both early and late samples (E–H). I Despite one outlier, overall Kim1 expression increased in late-exposed compared to controls at 6 weeks of age, although overall expression decreased from acute injury phase. J Evaluating the percent fold change from the median control value, we identified a larger percent change in Kim1 expression in the late-exposed compared to early-exposed rabbits.
