Fig. 5 | Scientific Reports

Fig. 5

From: Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models

Fig. 5

(A) The brain tumour models were induced using the stereotaxic injection surgery. The tumours were confirmed with MR images prior to the MR-guided FUS treatment. Three weekly treatments were performed at the designed stage. (B) The procedure of sonodynamic therapy. In brief, the sonodynamic agent, 5-ALA, was administered intravenously 6 h before the FUS sonication. (C) A representative treatment planning image was shown, and the FUS targets covering the tumour volume were placed.

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