Fig. 8

Expression and functional analysis of SLC3A2 in ECs. (A) Proportion of High-TIMP1 EC and Low-TIMP1 EC groups in OA and control samples. (B) UMAP representation showing the gene distribution of High-TIMP1 EC and Low-TIMP1 EC groups. (C) Expression level of SLC3A2 among the 6 OA chondrocyte cell types in OA and control samples, respectively. (D) KEGG pathway analysis between High-TIMP1 EC and Low-TIMP1 EC groups. (E) GO functional analysis between High-TIMP1 EC and Low-TIMP1 EC groups. (F) Hallmark gene set enrichment analysis between High-TIMP1 EC and Low-TIMP1 EC groups. (G) Communication networks among different cell types. (H) Hallmark gene set enrichment analysis among different cell types. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.