Fig. 11
Effect of Pazopanib on proliferation, apoptosis and migration in GBM tumor cell lines and HT-22 cells. (A) Cell proliferation were detected by CCK-8 in lines-U87 and SW68, ***P < 0.001. (B) Cell apoptosis were detected by flow cytometry in U87 and SW68 cells, **P < 0.01, ***P < 0.001. (C) Cell migration were detected in U87 and SW68 cells, ns P > 0.05. (D) Cell proliferation were detected by CCK-8 in HT-22 cells. **P < 0.01. (E) Cell apoptosis were detected by flow cytometry in HT-22 cells under the co-intervention of RA and PAZ, ***P < 0.001. All experiments were repeated three times. Indicates a significant difference compared to other groups in a two-way ANOVA followed by Tukey’s test (P < 0.05).
