Fig. 6

Heatmap of 23 candidate genes based on the log2FC value. Different colors indicate the log2FC value of this gene in the 5 transcriptome data sets (human NTD n = 3, human GBM n = 163, NTD mouse E10.5 n = 9, NTD mouse E9.5 n = 9, NTD mouse E8.5 n = 9). The figure shows 23 genes with the same expression trend, that is, the expression is up-regulated or down-regulated in all 5 transcriptome data sets.