Fig. 5 | Scientific Reports

Fig. 5

From: Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning

Fig. 5

Validation expression levels of CCR7, IL2RG, and PLEK in mice. (A-F) Evaluating of psoriasis mice model using topical IMQ (N = 6). (G-I) RNA expression levels of IL2RG, CCR7, PLEK, and IL17 in the mice by RT-qPCR (N = 6). (J-K) Protein expression levels of IL2RG, CCR7, and PLEK in the mice (N = 6). (L-M) RNA expression level and serum level of IL-17A in the mice detected by RT-qPCR and ELISA (N = 6). IMQ: imiquimod cream. Scale bar = 400 μm. ** P < 0.01; *** P < 0.001.

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