Fig. 6 | Scientific Reports

Fig. 6

From: Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning

Fig. 6

Blockade of PLEK alleviates IL-17A-related inflammation and psoriasis in mice skin tissues. (A-F) Evaluating of psoriasis mice model using topical IMQ (N = 6). (G-H) RNA and protein expression levels of PLEK in the mice skin tissues by RT-qPCR and WB (N = 6). (I-J) RNA expression level and serum level of IL-17A in the mice skin tissues detected by RT-qPCR and ELISA (N = 6). IMQ: imiquimod cream. Scale bar = 400 μm. *** P < 0.001.

Back to article page