Fig. 8
From: Investigating the PI3K/AKT/mTOR axis in Buzhong Yiqi Decoction’s anti-colorectal cancer activity
BZYQD impeded CD86 levels and promoted CD206 levels in M1 macrophages. (A, B) Flow cytometry was utilized for both qualitative and quantitative analysis of tumor-associated macrophages (TAMs). (C) The cytotoxic effect of BZYQD on TAMs following 24 h of treatment was assessed in vitro using a CCK-8 assay. (D, E) The analysis shows the mean fluorescence intensity (MFI) with histograms for CD86 MFI and CD206 MFI. (F, G) The impact of BZYQD on the secretion of IL-6 and IL-10 in activated macrophages was evaluated. Data are expressed as mean ± SEM (n = 3). **P < 0.01 vs. the Con group, ##P < 0.01 vs. the M1 group.
