Fig. 1

Differential Expression and Interaction Analysis of Disulfidptosis-Related Genes in UC Across Multiple Datasets. (A–D) Heatmaps showing the expression patterns of differentially expressed genes (DEGs) in UC and control samples across four datasets: GSE87473 (A), GSE38713 (B), GSE75214 (C) and GSE92415 (D). Red indicates upregulation, and blue indicates downregulation. (E) Venn diagram illustrating the overlap of DEGs among the four datasets, highlighting consistently dysregulated genes. (F) Circular plot depicting the genomic locations of six common DEGs, providing insights into their chromosomal distribution. (G) Protein–protein interaction (PPI) network visualizing functional relationships among DEGs, suggesting potential regulatory pathways involved in UC. All results were generated with the R software (version: 4.3.1).