Fig. 6

YKL-40 overexpression enhances CD3 + and CD68 + immune cell infiltration in melanoma tumors. Immunohistochemical analysis of CD3+ (T cells) and CD68+ (macrophages) immune cell infiltration in melanoma tumors from control and YKL-40-overexpressing tumors. DAPI (blue) was used to stain cell nuclei. (bars, SD; t-test; ***P < 0.001; n = 3; Scale bar represents 50 μm).