Fig. 6 | Scientific Reports

Fig. 6

From: Zwitterionic poly-carboxybetaine-dexamethasone conjugates do not alleviate cartilage degeneration and synovitis in the collagenase-induced osteoarthritis model in rats

Fig. 6

DEX and pCBAA-DEX have no effect on gait asymmetry and weight loss: (A) Visually observed gait asymmetry in the animals was no longer detected beyond day 7 of the study. There are no statistically significant differences between saline, DEX and pCBAA-DEX groups. The vertical lines represent the timepoints for intraarticular injection (day 0 & 2: collagenase, day 4: treatments). (B) All treatment groups show a similar decrease in weight of 2–4% between days 6 and 10 of the study. Beyond day 10, the animals start to regain weight and follow a similar trajectory as the naïve animals. The solid line represents the average value, the area the standard deviation.

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