Fig. 7

Patient demographics. A total of 20 control and 20 age-matched PD patients were included in the study with an average age of approximately 80 years. A greater prevalence of males in the PD group was noted, but no significant gender effect on the brain Cx43 levels was observed. Braak stages for Lewy Body / α-synuclein, amyloid, and tau, as well as cerebral amyloid angiopathy scores, were recorded. Listed causes of death were summarised with cardiovascular and pulmonary causes most prevalent in the controls, and PD or PD-related dementia being the leading cause of death in the patient group. Statistical analysis: t-tests; error bars: SEM. PD—Parkinson’s disease; Cx43—connexin 43; LB—Lewy body; a-syn—α-synuclein.