Fig. 2 | Scientific Reports

Fig. 2

From: Irradiated umbilical cord mesenchymal stem cell-coated high oxygen-permeable hydrogel lenses inhibit corneal inflammation and neovascularization after corneal alkali burns

Fig. 2

Images of AS-OCT images and HE-stained corneas in each group on day 18. AS-OCT imaging revealed that the normal corneal surfaces were smooth and that the corneal stroma was generally homogeneous. In contrast, the corneas in the other groups displayed varying degrees of edema or ulceration. Among these groups, the radiation-treated UCMSC lenses effectively reduced corneal edema and prevented ulcer formation (as depicted in (A)). A bar plot of the central corneal thickness is shown in (B). Images of corneal HE-stained tissues from the various groups under a light microscope showed that the inflammation of the corneal tissue in the blank lens group and the untreated group was more severe than that in the other groups ((C): magnification×100; (D): magnification×200). The statistical analysis indicated significant differences at *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.

Back to article page