Fig. 7 | Scientific Reports

Fig. 7

From: Irradiated umbilical cord mesenchymal stem cell-coated high oxygen-permeable hydrogel lenses inhibit corneal inflammation and neovascularization after corneal alkali burns

Fig. 7

Immunohistochemistry, ELISA and PCR analysis of IL-17 in injured rabbit corneas. Compared with that in the corneas of the left eye, the expression of the IL-17 protein in the blank lens group was dramatically greater, and the IL-17-positive cells were mainly concentrated in the corneal stroma (A1,B1), magnification×400; (A2, B2), magnification×200.). The concentrations of IL-17 (C) and the mRNA (D) levels of CD3G, LAT, STAT1, IL-1B, IL-6, CCR6, IL-17 A, IFN-γ, IL-23, and IL-4 in the blank lens group and the radiation-treated UCMSC lens group were analyzed on day 18. A t test was carried out to compare the differences between the blank lens group and the radiation-treated UCMSC lens group. The statistical significance is represented as follows: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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