Table 7 Toxicity categories and LD50 mg/kg values for selected chemical components derived from Melissa officinalis.
From: Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
Compound | LD50 (mg/kg of body weight) | Toxicity class |
|---|---|---|
5-Methyl-5Â H-naphtho[2,3-c] carbazole | 347 | 4 |
7Â H-Dibenzo[b, g]carbazole, 7-methyl | 347 | 4 |
Hesperidin | 12,000 | 6 |
Luteolin-7-glucoside-3′-glucuronide | 5000 | 5 |
Sagerinic acid | 2000 | 4 |
Betulinic acid | 2610 | 5 |
Ursolic acid | 2000 | 4 |
Oleanolic acid | 2000 | 4 |
2-[4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)hexa-1,3,5-trienyl]cyclohex-1-en-1-carboxaldehyde | 10,000 | 6 |
Melitric acid A | 500 | 4 |
Nepetoidin A | 2980 | 5 |
Rosmarinic acid | 5000 | 5 |
[5,9-Dimethyl-1-(3-phenyl-oxiran-2-yl)-deca-4,8-dienylidene]-(2-phenyl-aziridin-1-yl)-amine | 400 | 4 |
Methyl arachidonate | 20,000 | 6 |
Z, Z,Z-1,4,6,9-Nonadecatetraene | 1680 | 4 |
Pregan-20-one, 2-hydroxy-5,6-epoxy-15-methyl | 4290 | 5 |
N, N’-Bis(Carbobenzyloxy)-lysine methyl(ester) | 1000 | 4 |
[1,3,5]Triazino[1,2-a][1,3]benzimidazol-2-amine, 1,4-dihydro-4-(2-methylphenyl)- | 1100 | 4 |
