Fig. 4
Genetic landscape of tumors with different risk groupings in the IRGP model (high-risk group: 180 cases, low-risk group:107 cases). (A) Drugs affected by mutated genes in the low-risk group. (B) Drugs affected by mutated genes in the high-risk group. (C) GO enrichment analyses of low-risk groups. (D) GO enrichment analyses of high-risk groups. (E) The heatmap illustrates the co-occurrence and mutually exclusive mutations in low-risk groups. (F) The heatmap illustrates the co-occurrence and mutually exclusive mutations in high-risk groups. (G,H) Comparison of TMB between patients in the high- and low-riskscore groups. (I) The mutational landscape of low-risk groups and high-risk groups.
