Fig. 3: Heterogeneous responses of RVT in different regional lymph nodes. | npj Precision Oncology

Fig. 3: Heterogeneous responses of RVT in different regional lymph nodes.

From: Different pathologic responses to neoadjuvant anti-PD-1 in primary squamous lung cancer and regional lymph nodes

Fig. 3

a Histological morphology and immune cell distribution in an inflamed morphological phenotype of RVT in one resected N1 lymph node, showing infiltration with many immune cells (H&E), high intensity of CD8 + T cells, infiltration of CD4 + T cells, CD20 + B cells, and CD163 + histocytes in CK(AE1/AE3) + RVT cell nests. b Histological morphology and immune cell distribution in a non-inflamed morphological phenotype of RVT in one resected N2 lymph node from the same patient, showing infiltration of few immune cells (H&E), low intensity of CD8 + T cells, no infiltration of CD4 + T cells, CD20 + B cells, and CD163 + histocytes in CK + RVT cell nests. Original magnification: ×200.

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