Fig. 6: Detailed influence of computation rules and VAF cut-off. | npj Precision Oncology

Fig. 6: Detailed influence of computation rules and VAF cut-off.

From: Enhancing the quality of panel-based tumor mutation burden assessment: a comprehensive study of real-world and in-silico outcomes

Fig. 6

a Importance of variant classifications and filtering rules. The “≥1” column describes the number of panels which had at least one parameter combination with top performance including this rule. The “100%” column describes the number of panels for which all the parameter combinations with top performance included this rule. The “0%” column describes the number of panels for which all the parameter combinations with top performance all excluded this rule. The “Matters? (%)” column describes the percentage of panels that significantly affected by this rule. b Panel performance with five VAF cut-offs under four different tumor purity conditions.

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