Table 3 Systematic removal of genes from the UAB36

From: Development of a polygenic score predicting drug resistance and patient outcome in breast cancer

 

METABRIC

GSE9195

Variables

HR

P

HR

P

UAB36

1.28

2.34E−02

3.92

4.38E−02

UAB36-1 (GNG12)

1.32

9.94E−03

4.75

2.52E−02

UAB36-2(DCBLD2, TM4SF1)

1.31

1.15E−02

4

4.02E−02

UAB36-2(ARHGAP29, TM4SF1)

1.32

9.56E−03

4.8

2.19E−02

UAB36-3(FAM129B, ANXA2, S100A10)

1.39

2.61E−03

4.4

3.04E−02

  1. Multivariate Cox regression of UAB36 with established gene signatures and clinical risk factors in the METABRIC cohort and GSE9195 cohort.