Fig. 3: Retrospective case analysis correlating treatment response with QPOP-defined outcomes in a HES patient.

a Treatment timeline for the patient. The green circle denotes the time point at which QPOP analysis was performed. b Forest plot depicting QPOP-derived normalized cell viability (NCV) scores (mean ± SD) of single and combination agents in prior lines of treatment. c Parabolic response surface map of drug interaction between gemcitabine and docetaxel. d Computed tomography (CT) imaging of the liver lesion before and after treatment with (i) doxorubicin, (ii) gemcitabine and docetaxel, and (iii) pazopanib treatment.