Table 6 Lung nodule detection performance of AI-assisted product

From: Spatial resolution enhancement using deep learning improves chest disease diagnosis based on thick slice CT

Variables

Sensitivity, % [No./total No.]

95% CI, %

Pairwise comparisons

   

P value

P value

P value

P value

All Nodules (N = 1567)

  

Real 1-mm

Real 5-mm

BIS 1-mm

DLS 1-mm

Real 1-mm

84.7 [1327/1567]

82.8–86.5

Ref

   

Real 5-mm

35.4 [554/1567]

33.0–37.8

<0.001*

Ref

  

BIS 1-mm

51.9 [813/1567]

49.4–54.4

<0.001*

<0.001*

Ref

 

DLS 1-mm

69.9 [1096/1567]

67.6–72.2

<0.001*

<0.001*

<0.001*

Ref

Solid nodules (N = 968)

  

Real 1-mm

Real 5-mm

BIS 1-mm

DLS 1-mm

Real 1-mm

82.3 [797/968]

80.0–84.8

Ref

   

Real 5-mm

30.9 [299/968]

28.1–34.0

<0.001*

Ref

  

BIS 1-mm

53.7 [520/968]

50.6–56.8

<0.001*

<0.001*

Ref

 

DLS 1-mm

71.1 [688/968]

68.2–73.9

<0.001*

<0.001*

<0.001*

Ref

Subsolid nodules (N = 108)

  

Real 1-mm

Real 5-mm

BIS 1-mm

DLS 1-mm

Real 1-mm

85.2 [92/108]

77.9–91.7

Ref

   

Real 5-mm

31.5 [34/108]

23.3–40.7

<0.001*

Ref

  

BIS 1-mm

59.3 [64/108]

49.5–69.2

<0.001*

<0.001*

Ref

 

DLS 1-mm

83.3 [90/108]

76.4–89.9

>0.99

<0.001*

<0.001*

Ref

Calcific nodules (N = 491)

  

Real 1-mm

Real 5-mm

BIS 1-mm

DLS 1-mm

Real 1-mm

89.2 [438/491]

86.4–91.7

Ref

   

Real 5-mm

45.0 [221/491]

40.5–49.2

<0.001*

Ref

  

BIS 1-mm

46.6 [229/491]

42.2–51.2

<0.001*

>0.99

Ref

 

DLS 1-mm

64.8 [318/491]

60.6–69.0

<0.001*

<0.001*

<0.001*

Ref

  1. AI Artificial Intelligence, BIS bicubic interpolation synthetic, DLS deep learning synthetic, Ref reference.
  2. *Statistically significant difference at a significance level of p < 0.05.