Fig. 4: Future directions in algorithms for predicting drug synergy and antagonism based on multi-omics data.
From: Computational frameworks transform antagonism to synergy in optimizing combination therapies

Five key future directions in drug combination therapy research, highlighting the integration of drug resistance mechanisms, pharmacokinetics, immunotherapy optimization, microbiome analysis, and adverse reaction management. Common side effects are illustrated for different organ systems. This figure was created based on the tools provided by Biorender.com (accessed on 4/9/2024).