Fig. 1: Asymmetric cyclopropanation between olefin and diazo compound.
From: Organocatalytic regio- and stereoselective cyclopropanation of olefins
a, State-of-the-art approaches to cyclopropanation of olefin with diazo compounds using metal catalysts, enzyme catalysts and the catalytic cycle. b, Our design, featuring catalytic asymmetric insertion of a diazo compound to an in situ-generated radical cation intermediate. L, ligand; M, metal.
