Extended Data Fig. 1: Inhibition of MT1-MMP improves metabolic parameters in mice with high fat diet-induced obesity.
From: Body weight regulation via MT1-MMP-mediated cleavage of GFRAL
Body weight (a), average daily food intake (b), blood glucose concentration (c), triglyceride, cholesterol concentrations (d) and fat mass (e) of male mice with high fat diet-induced obesity after receiving (twice a week) treatment with either 3A2 antibody or control IgG for 4 weeks (n=8). Data are reported as average ± s.e.m. *P < 0.05; **P < 0.01; ***P < 0.001. two-way ANOVA for (a), two-sided unpaired t-test for (b-e).
