Extended Data Fig. 2: Inhibition of MT1-MMP improves metabolic parameters in ob/ob mice.
From: Body weight regulation via MT1-MMP-mediated cleavage of GFRAL
Body weight (a), average daily food intake (b), blood glucose concentration (c) and insulin level (d) of male ob/ob mice after receiving (twice a week) treatment with either 3A2 antibody or control IgG for 4 weeks (n=8). Data are reported as average ± s.e.m. two-sided unpaired t-test for (a-d).
