Extended Data Fig. 5: C/EBPβ in high glucose or oxidized LDL treated primary GECs and podocytes.
From: Genetic susceptibility to diabetic kidney disease is linked to promoter variants of XOR

a) Representative immunofluorescence staining for C/EBPβ (green) and CD31 (magenta) in primary glomerular endothelial cells from B6-XorWT and B6-Xorem1 mice (n = 3), treated with control normal glucose (NG), or high glucose (HG, 30 mM) for 24 hours showing nuclear translocation. Bar=20μm. b) C/EBPβ (green) and synaptopodin (red) in primary podocytes from B6-XorWT and B6-Xorem1 mice (n = 3), treated as in a). Bar=20μm. These are representative images from 3 independent experiments performed in primary cells grown from 3 separate B6-XorWT and 3 separate B6-Xorem1 mice.