Extended Data Fig. 4: Proteome analysis of liver and muscle of adult-onset β-cell-specific inceptor KO vs. WT mice. | Nature Metabolism

Extended Data Fig. 4: Proteome analysis of liver and muscle of adult-onset β-cell-specific inceptor KO vs. WT mice.

From: Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity

Extended Data Fig. 4

Principle component analysis (PCA) of all tissue samples (a). Clustering of quadriceps muscle (left) and liver (right) samples as well as z-scored protein intensities. Bar beneath the clustering indicates genotype (WT: white, KO: red) (n = 4 KO, n = 5 WT for muscle, n = 5 each genotype for liver) (b). Volcano plots of the same organs as in (b) ProteinGroups only found in one condition are indicated in black (c) (n = 5 each genotype).

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