Extended Data Fig. 3: Significant enrichment of iSPN signature gene expression in sorted striatal subpopulations. | Nature Metabolism

Extended Data Fig. 3: Significant enrichment of iSPN signature gene expression in sorted striatal subpopulations.

From: Impaired striatal glutathione–ascorbate metabolism induces transient dopamine increase and motor dysfunction

Extended Data Fig. 3

a) Heatmap representation of average expression values of 48 SPN marker genes23 in the different sorted striatal populations. The black frame highlights the largest cluster (n.1). b) Bubble plot visualising DAVID gene ontology (GO) analysis using the enriched gene set from cluster 1/2 in (a). Significant enrichment of GO terms associated with critical functions of iSPN+ is shown as a colour gradient with highly significant enriched terms in purple and low ones in sky blue. The bubble size indicates the percentage of gene clusters. Related to Fig. 3.

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