Extended Data Fig. 5: The effects of acute CNO administration are recapitulated in male Gq-NGOxtr mice maintained on high fat diet. | Nature Metabolism

Extended Data Fig. 5: The effects of acute CNO administration are recapitulated in male Gq-NGOxtr mice maintained on high fat diet.

From: Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice

Extended Data Fig. 5

Impact of CNO (0.3 mg/kg i.p.) or saline administered at ZT11 on hourly (a) food and (b) water intake, (c) oxygen consumption (VO2), (d) respiratory exchange ratio (RER), (e) body temperature, (f) systolic blood pressure (SBP), (g) heart rate (HR) and (h) change in body weight in Gq-NGOxtr mice (n = 7). Data represented as mean ± SEM. (a-g) Within subjects two-way repeated measures ANOVA with Šídák’s multiple comparisons test, (h) Paired, two-tailed t-test, *p < 0.05.

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