Extended Data Fig. 6: Efficacy of immune checkpoint therapy (ICT) and treatment effects on immune microenvironment. | Nature Cancer

Extended Data Fig. 6: Efficacy of immune checkpoint therapy (ICT) and treatment effects on immune microenvironment.

From: Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer

Extended Data Fig. 6

A. Heatmap of six immune cell clusters with unique signature genes. B. UMAP projection of T cell clusters (top) and violin plots displaying relative expression of representative genes and functional markers used for identification of T cell clusters (bottom). C. Heatmap of ten T cell clusters with unique signature genes. D. UMAP projection of neutrophil/granulocyte clusters (top) and violin plots displaying relative expression of representative genes and functional markers used for identification of neutrophil/granulocyte clusters (bottom).

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