Extended Data Fig. 4
a. Volcano plots of the PIK3R5-interacting protein pulled down in OCI-AML2, MV4-11, and NOMO-1 cells compared to control. DIA MS data were processed using Spectronaut with default factory setting providing an unpaired t-test p-value for quantified proteins. b. Ranking of proteins with positive infinite ratios (only identified in PIK3R5 pull down) according to the number of peptides identified. Only proteins with a z-test score > 0.95 were included for further analysis. c. Network corresponding to Fig. 3a depicting, in two colors, the PIK3R5-interacting proteins identified in two cell lines (in yellow) or all three cell lines (in orange).
