Extended Data Fig. 9
a-b. Toxicity profile of ARM165 treatment in naive mice. Mice were treated with IV injection of 0.051 mg/kg ARM165 for seven consecutive days. Individual mouse weight was measured daily (n = 5 mice per group) (a) and the proportion of each indicated hematopoietic cell fraction (b) was established in blood using an MS9 instrument, and in bone marrow (BM) and spleen (SP) by flow cytometry (n = 10 mice per group). Error bars represent mean ± SD. P-values calculated using Mann-Whitney and reported on the figure panel.
