Extended Data Fig. 6: The impact of perturbing mitochondria function on epigenetic aging.
From: The relationship between epigenetic age and the hallmarks of aging in human cells

Mitochondrial activity of primary human keratinocytes was either compromised by treatment with CCCP or enhanced by culturing in Bezafibrate. DNA methylation profiles of these cells and their untreated controls were analyzed by four different epigenetic clocks (a-d).