Extended Data Fig. 3: The impact of prevention of replicative senescence on epigenetic aging.
From: The relationship between epigenetic age and the hallmarks of aging in human cells

Measurement of EpiAge of human neonatal primary fibroblasts transduced with hTERT-expressing vectors or empty vector at various time point during their culture until senescence (S) of the control cells. DNA methylation profiles were analyzed by four different epigenetic clocks (a-d). Similar approach was employed with adult human coronary artery cells (e-h).