Extended Data Fig. 4: Rapamycin treatment reduces ISC mitoses in wDah females but not in males.
a,b, Rapamycin treatment (200 µM) reduced the number of pH3 + cells in females, to a similar level as in untreated males, while it did not affect the number of pH3 + cells in males, (a) at 10 days of age, and (b) at 50 days of age (10 days n = 15-24 intestines, 50 days n = 10-12 intestines, two-way ANOVA, interaction 10 days p < 0.001, 50 days p < 0.01; post-hoc test). Data are presented as mean values ± s.e.m.
