Extended Data Fig. 6: Rapamycin treatment increases expression of histone H3, histone H4 and Bchs in intestines of females but not in males. | Nature Aging

Extended Data Fig. 6: Rapamycin treatment increases expression of histone H3, histone H4 and Bchs in intestines of females but not in males.

From: Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin

Extended Data Fig. 6

a, The expression of histones H3 and H4 in intestines of wDah females was lower than in males, and rapamycin treatment (200 µM) increased it, at 10 days of age (n = 4 biological replicates of 10 intestines per replicate, two-way ANOVA, H3, interaction p < 0.05, H4, interaction p < 0.001; post-hoc test). b, The expression of Bchs in intestines of wDah females was lower than in males, and rapamycin treatment (200 µM) increased it, at 10 days of age (n = 4 biological replicates of 10 intestines per replicate, two-way ANOVA, interaction p > 0.05; post-hoc test). Data are presented as mean values ± s.e.m.

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