Extended Data Fig. 9: Dimorphic responses to rapamycin in mice tissues. | Nature Aging

Extended Data Fig. 9: Dimorphic responses to rapamycin in mice tissues.

From: Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin

Extended Data Fig. 9

a-c, The expression of p62/SQSTM1 in the heart, kidney, and spleen of female and male mice (n = 6 biological replicates of one mouse per replicate, two-way ANOVA, Heart: treatment p < 0.01, sex p = 0.64, interaction p = 0.74, post-hoc test; Kidney: treatment p < 0.05, sex p = 0.91, interaction p = 0.25, post-hoc test; Spleen: treatment p = 0.13, sex p = 0.66, interaction p = 0.57, post-hoc test). All mice were sacrificed and tissues were collected at 12 months of age. Data are presented as mean values ± s.e.m.

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